Tag Archives: Depression

Maternal Depression, But Not Exposure to SSRIs, Associated with Worse Executive Functioning in Children  

While we have considerable data on the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy, most of this research focuses on the risk of congenital malformations in exposed children.  We have far less information regarding the long-term effects of SSRI antidepressants on neurodevelopmental outcomes in exposed children. A recent study looks at executive functioning… Read More »

Oral Allopregnanolone Analogue for Postpartum Depression Treatment

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed… Read More »

Hearing Loss Can Increase Your Risk Of Depression

Research has discovered that older people with age-related hearing loss experienced more depressive symptoms; the more the hearing loss, the more the risk of having symptoms of depression. The results indicate that treating age-related hearing loss, an under recognized and under treated condition among all older people, could be one method to help prevent late-life… Read More »